Reishi Mushroom extract
Item: NL-012
Grade: 40% Polysaccharides
Botanical origin: Ganoderma Lucidum
CAS NO.: 57-87-4
Molecular formula:C28H44O
Appearance: Fine brown yellow powder
Type of extraction: Ethanol/water
Solubility: Good soluble in water
Reishi mushroom(Lingzhi) encompasses several fungal species of the genus Ganoderma, and most commonly refers to the closely related species, Ganoderma lucidum and Ganoderma tsugae. G. lucidum enjoys special veneration in East Asia, where it has been used as a medicinal mushroom in traditional Chinese medicine for more than 2,000 years, making it one of the oldest mushrooms known to have been used medicinally. Because of Reshi mushroon's presumed health value and apparent absence of side-effects, it has attained a reputation in the East as the ultimate herbal substance. Reshi mushroom is listed in the American Herbal Pharmacopoeia and Therapeutic Compendium.
Reshi mushroom may possess anti-tumor, immunomodulatory and immunotherapeutic activities, supported by studies on polysaccharides, terpenes, and other bioactive compounds isolated from fruiting bodies and mycelia of this fungus (reviewed by R. R. Paterson and Lindequist et al.. It has also been found to inhibit platelet aggregation, and to lower blood pressure (via inhibition of angiotensin-converting enzyme), cholesterol, and blood sugar.
Laboratory studies have shown anti-neoplastic effects of fungal extracts or isolated compounds against some types of cancer, including epithelial ovarian cancer. In an animal model, Ganoderma has been reported to prevent cancer metastasis, with potency comparable to Lentinan from Shiitake mushrooms.
The mechanisms by which Ganoderma lucidum may affect cancer are unknown and they may target different stages of cancer development: inhibition of angiogenesis (formation of new, tumor-induced blood vessels, created to supply nutrients to the tumor) mediated by cytokines, cytoxicity, inhibiting migration of the cancer cells and metastasis, and inducing and enhancing apoptosis of tumor cells. Nevertheless, Ganoderma lucidum extracts are already used in commercial pharmaceuticals such as MC-S for suppressing cancer cell proliferation and migration.
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