Applications: 4-Dimethylaminopyridine is widely used as a catalyst in chemical synthesis, particularly in the ...    More ...

Applications:
4-Dimethylaminopyridine is widely used as a catalyst in chemical synthesis, particularly in the synthesis of organic pharmaceuticals, pesticides, dyes, and food additives, for acylation, carbonylation, etherification, and esterification. 4-Dimethylaminopyridine is a novel and highly efficient catalyst widely used in chemical synthesis in recent years. Its structure utilizes the resonance between the electron-donating dimethylamino group and the parent ring (pyridine ring), strongly activating the nitrogen atom on the ring for nucleophilic substitution. It significantly catalyzes acylation (phosphorylation, sulfonylation, and carbonylation) reactions of sterically hindered and low-reactivity alcohols and amines, with an activity approximately 10⁴–6 times that of pyridine. It exhibits high catalytic activity in various types of reactions, including acylation, alkylation, etherification, esterification, and transesterification, in organic synthesis, pharmaceutical synthesis, pesticides, medicines, dyes, fragrances, polymer chemistry, and analytical chemistry, significantly improving yields.
                                           Items
                                          

Standard

                     
                                      Appearance
                                          

White crystal

                     
                                      Assay
                                          ≥99.0%
                     
                                      Water
                                          ≤0.1%
                     
                                      Water insoluble
                matter
                                          ≤0.1%
                     
                                      Melting range
                                          111~114℃
                     
    
Less ...