Uses: Sulfadiazine sodium is primarily used to treat meningitis caused by susceptible Neisseria ...    More ...

Uses:
Sulfadiazine sodium is primarily used to treat meningitis caused by susceptible Neisseria meningitidis. It can also be used to treat: 1. Acute bronchitis and mild pneumonia caused by susceptible Haemophilus influenzae, Streptococcus pneumoniae, and other streptococci. 2. Nocardia asteroides. 3. Adjunctive therapy in the treatment of chloroquine-resistant malignant malaria. 4. In combination with pyrimethamine for the treatment of toxoplasmosis caused by Toxoplasma gondii.
                                           Items
                                          

Standard

                     
                                      Appearance
                                          White or almost white crystalline or powder
                     
                                      Identification   A
                                          The infrared absorption spectrum concordant with the spectrum of Sulfadiazine   CRS
                     
                                      Identification   B
                                          Test for sodium
                     
                                      Solubility
                                          Freely soluble in water,slightly soluble in alcohol
                     
                                      Heavy Metals
                                          Not more than 10 ppm
                     
                                      Melting range
                                          250°C-254°C
                     
                                      Clarity of the solution
                                          Clear
                     
                                      Acidity
                                          PH=9.6-10.5
                     
                                      Selenium
                                          Not more than 30 ppm
                     
                                      Loss on drying
                                          Not more than 0.5%
                     
                                      Assay
                                          NLT 99.0% and NMT 100.5% ofC10H9N4O2NaS,
                 calculated on the dried basis
                     
    
Less ...