1 TIME - XL - H.A. filler: A beauty innovation that brings volume, youthfulness, and collagen stimulation to the skin. This remarkable filler is based on advanced hyaluronic acid technology, offering exceptional elasticity and preventing wrinkles. With its high moldability, structural stability, and long-lasting effects, it's a true game-changer in the world of skincare. Experience the artistry of H.A. filler as it enhances skin volume, smooths away fine lines, and revitalizes your natural beauty, all while maintaining a natural and harmonious appearance. Embrace the beauty of H.A. filler and revel in its ability to create plump, firm, and timeless skin
Indication:
It is used for the reduction of deep wrinkles
Restoration of lost volume
Volumetry
Nose correction
Treatment areas:
Forehead
Cheekbones,
Nose
Double chin

Effects:
It Improves skin elasticity and fine wrinkles
It has natural results with a smooth
This product has long-lasting effects


Packaging:
1 ml x 1syringe
Needle size 28G
 
Introduction:
 
Celmade 1 Time Filler is a product designed for tissue regeneration and is based on hyaluronic acid, a crucial component found in various tissues of the body.
Hyaluronic Acid Structure and Characteristics:
 
Hyaluronic acid is a linear high polysaccharide composed of N-acetyl, D-glucosamine, and D-glucuronic acid.
It plays a vital role in maintaining tissue structure and facilitating the transportation of metabolites by binding water.
Hyaluronic acid is metabolized by somatic cells and can be used in both soft and hard tissue applications.
Roles of Hyaluronic Acid:
 
Hyaluronic acid serves structural and biological roles in the body.
Structurally, it is a key component of the extracellular matrix (ECM) and acts as a natural moisturizing agent.
Biologically, it influences cellular functions, including wound healing, embryogenesis, bacteriostatic effects, and bone restoration.
Distribution of Hyaluronic Acid in the Body:
 
Hyaluronic acid levels in various body fluids vary, and it decreases with age and chronic diseases.
 
          
Celmade 1 Time Filler Technology:
 
The product utilizes differentiated manufacturing technology and exclusively uses hyaluronic acid from SHISEIDO, a renowned Japanese company.
It is available in different formulations, such as Celmade 1 Time Filler L, XL, and XXL, with and without lidocaine.
 
 
Efficacy and Benefits:
 
Celmade 1 Time Filler offers long-term elasticity and maintains initial volume due to its unique network structure.
It demonstrates excellent syringeability, indicating easy and high elasticity.
In in-vivo safety experiments on mice and rats, the product exhibited favorable tissue responses and stability.
Complex viscosity and in-vitro enzyme stability tests showed superior results compared to other products.
The product has a low protein load and minimal endotoxin levels, ensuring excellent safety.
Celmade 1 Time Filler provides softness, volume, cohesiveness, durability, and stability after, with a duration of 12-18 months.
 
 
 
 
Instructions for Use:
 
It emphasizes the importance of checking the package for damage and verifying the expiry date.
Users are advised to wear surgical gloves and clean the surgical area before.
After opening the package, the contents should be used promptly and disposed of properly.
 
 
Certainly, here is a detailed summary of the methods for various facial areas using the Celmade 1 Time Filler:
 
Forehead Augmentation:
- Procedure to make a low forehead look solid.
- Use a big needle with a big diameter and about 3.5cm long length or using a cannula after centesis of the skin.
- to medium or lower layer of dermis using high viscosity filler.
- In case of needing a big augmentation, use super high viscosity filler to the layer of fat.
 
Temple Augmentation:
- Upheave hollow temple to make the lower part of the cheek look relatively small.
- Topical anesthesia (spread type) is sufficient.
- using linear threading technique or fan technique on the backside of the hairline.
- Use medium viscosity filler for women and high viscosity filler for men or individuals with thick skin.
 
Cheek Augmentation:
- Fill hollow cheeks to make the face look younger.
- Topical anesthesia or infiltration anesthesia is recommended.
- Use a cannula for a wide range.
- using linear threading technique or fan technique.
- For big augmentations, below the jaw using a cannula or 18G needle, contacting the bone.
 
Paranasal Augmentation:
- Augment the area around the nose.
- Anesthesia may not be needed.
- high viscosity filler after forming a base beneath the dermis.
- Implement infiltration anesthesia when needed.
 
Chin Augmentation:
- Use for slight under-jaw microsomia or asymmetry.
- Decide the filler type based on skin thickness and augmentation amount.
- Infiltration anesthesia may be needed.
- to medium or lower layer of corium using high viscosity filler.
- Fix with a 27G needle if necessary.
 
Vermillion Augmentation (Lips):
- Be cautious as lips have many blood vessels and superficial nerve endings.
- Use topical anesthesia.
- to the border from lips to mucous membrane using bevel-up.
- within 2mm of the lower part of the epidermis.
 
Nose Augmentation:
- Use to enhance the nose's height.
- Anesthesia is not necessary but topical anesthesia can be applied.
- Use absorption or unabsorbable filler with high viscosity.
- Be cautious about wearing glasses and sleeping positions.
 


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